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The ONE - Optimal Nutrition Evaluation - consists of:

Metabolic Analysis measuring 39 key organic acids to evaluate gastrointestinal function,methylation, cellular energy production, neurotransmitter processing, and functional need for vitamins, minerals, and co-factors.

Amino Acid Analysis measuring 38 amino acids to evaluate dietary protein adequacy, digestion, absorption, amino acid transport, metabolic impairments, and nutritional deficits; including essential vitamins, minerals, and amino acids.

Oxidative Stress Analysis is a sensitive tool to evaluate the body's anti-oxidant reserves and the presence of oxidative injury.

will they give you a treatment?

Got basically the same test done but through MetaMetrix

Got basically the same test done but through MetaMetrix

Hi moonman, did you already discuss these results on a different thread or post doctor's comments? Cheers.

B-Vitamins
Slight B-6 deficiency. Nothing that would cause issues though.

Inhibitory neurotransmitters tend to inhibit firing of neurons. The most important of these is GABA, which is synthesised from Glutamine in the presence of Active Vitamin B6 (P5P). GABA is examined more on the Adrenal and Endocrine System page. Taurine is another, which performs many vital functions in the body, including nutritional metal transport into the cells. Taurine is examined in more detail on the Nutritional Deficiencies page. The third main inhibitory neurotransmitter is the amino acid L-Glycine.

There are many substances in the body which act as antioxidants, but the three most important frontline antioxidants are
Co-enzyme Q10. This is the most important antioxidant inside mitochondria and also a vital molecule in oxidative phosphorylation. Co-Q10 deficiency may also cause oxidative phosphorylation to go slow because it is the most important receiver and donater of electrons in oxidative phosphyylation. People with low levels of Co Q 10 have low levels of energy.
superoxide dismutase (SODase) is the most important super oxide scavenger in muscles (zinc and copper SODase inside cells, manganese SODase inside mitochondria and zinc and copper extracellular SODase outside cells) , and
glutathione peroxidase. This enzyme is dependent on selenium and glutathione, a 3 amino acid polypeptide, and a vital free radiical scaveneger in the blood stream.

All the above antioxidants can be measured and I now almost routinely measure the frontline antioxidants, i.e. Co-enzyme Q10, superoxide dismutase(SODase) and glutathione peroxidase.
Co-enzyme Q10 My experience is that levels in CFS sufferers are almost always down and that they can be corrected by taking Co-enzyme Q10 300mg daily for three months, after which continue with a maintenance dose of 100mg.
Superoxide dismutase (SODase). Deficiency can explain muscle pain and easy fatigability in some patients. SODase is dependent on copper, manganese and zinc and I would expect this to be maintained in people taking my physiological mix of minerals (MMMs). However, when there is a deficiency, these minerals are taken separately. Experience shows that the best results are achieved by copper 1 mg in the morning, manganese 3 mg midday and zinc 30 mg at night. Low dose SODase may also result from gene blockages and these are also looked at when the SODase test is done. Blockages are most often caused by toxic stress, such as heavy metals and pesticides.
Glutathione peroxidase (GSH-Px). This is made up of glutathione, combined with selenium. There is a particular demand in the body for glutathione. Not only is it required for GSH-Px, which is an important frontline antioxidant, but it is also required for the process of detoxification. Glutathione conjugation is a major route for excreting xenobiotics. This means that if there are demands in one department, then there may be depletions in another, so if there is excessive free radical stress, glutathione will be used up and therefore less will be available for detoxification and vice versa. Of course, in patients with chemical poisoning or other such xenobiotic stress, there will be problems in both departments, so it is very common to find deficiencies in glutathione: If there is a deficiency of GSH-Px, then I recommend that patients eat a high protein diet (which contains amino acids for endogenous synthesis of glutathione), take a glutathione supplement 250mg daily, together with selenium 200mcg daily (which is present in my physiological mix of minerals MMMs).