PROPECIAHELP: Persistent Finasteride Propecia Proscar side effects info & discussion forum

Forum for men with PERSISTENT sexual, mental & physical side effects which CONTINUE DESPITE QUITTING Finasteride (Propecia, Proscar), a 5AR inhibitor drug for hair loss, prostate enlargement & prostate cancer.
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 Post subject: sleep disorder
PostPosted: Tue Oct 12, 2010 8:34 am 
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Joined: Thu Sep 09, 2010 3:52 pm
Posts: 288
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Can anyone tell me why Propecia can cause sleep disorder. Since I took Propecia I couldn't sleep well. I think I never had any deep sleep phases (REM phase).
Thanks for any thoughts.


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 Post subject: Re: sleep disorder
PostPosted: Tue Oct 12, 2010 8:46 am 
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Joined: Fri Nov 03, 2006 10:43 pm
Posts: 4416
Age: 31
Drug: Proscar
Usage: 11 months
Started: 0- 0-2004
Stopped: 0- 0-2005
Location: Propeciahelp
- Impairment of GABAergic system in the brain due to loss of 5AR-derived neurosteroid synthesis (Allopregnanolone/THDOC) while on the medication. GABA-A receptors/GABAergic system are involved in REM sleep.

- Decreased nitric oxide synthase. DHT has been found to mediate nitric oxide, and Finasteride inhibits DHT. Nitric Oxide is involved in the sleep/wake cycle.

http://www.medicalnewstoday.com/articles/51436.php

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 Post subject: Re: sleep disorder
PostPosted: Tue Oct 12, 2010 3:04 pm 
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Joined: Thu Sep 09, 2010 3:52 pm
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Thank you very much Mew. Great to have such a dedicated forum member like you.
All the best.


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