PROPECIAHELP: Persistent Finasteride Propecia Proscar side effects info & discussion forum

Interesting.

Are you going to try it liquidfirex?

You HPTA gets used to the extra T produced and will downregulate LH accordingly, so I think its important to cycle it. The Soviets used to use it for their olympic teams to raise T, back in the 70s.

I've tried it, does give a bit of a lift. It sensitizes the Ledyig cells to LH, making them more responsive (produce more T). Any time my T is on an upward slope I briefly feel better.

You HPTA gets used to the extra T produced and will downregulate LH accordingly, so I think its important to cycle it. The Soviets used to use it for their olympic teams to raise T, back in the 70s.

Stay away from green tea, it contains a 5a-reductase inhibitor.

Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. cAMP is an important signal carrier necessary for the proper biological response of cells to hormones and other extracellular signals. It is required for cell communication in the hypothalamus/pituitary gland axis and for the feedback control of hormones. It acts by activating protein kinase A.

Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men.
Godard MP, Johnson BA, Richmond SR. University of Kansas, Department of Health, Sport and Exercise Sciences, Applied Physiology Laboratory, Lawrence, KS 66045, USA. mgodard@ku.edu

Abstract

OBJECTIVE: This study examined the effect of forskolin on body composition, testosterone, metabolic rate, and blood pressure in overweight and obese (BMI > or = 26 kg/m(2)) men.

RESEARCH METHODS AND PROCEDURE: Thirty subjects (forskolin, n = 15; placebo, n = 15) were studied in a randomized, double-blind, placebo-controlled study for 12 weeks.

RESULTS: Forskolin was shown to elicit favorable changes in body composition by significantly decreasing body fat percentage (BF%) and fat mass (FM) as determined by DXA compared with the placebo group (p < or = 0.05). Additionally, forskolin administration resulted in a change in bone mass for the 12-week trial compared with the placebo group (p < or = 0.05). There was a trend toward a significant increase for lean body mass in the forskolin group compared with the placebo group (p = 0.097). Serum free testosterone levels were significantly increased in the forskolin group compared with the placebo group (p < or = 0.05). The actual change in serum total testosterone concentration was not significantly different among groups, but it increased 16.77 +/- 33.77% in the forskolin group compared with a decrease of 1.08 +/- 18.35% in the placebo group.

DISCUSSION: Oral ingestion of forskolin (250 mg of 10% forskolin extract twice a day) for a 12-week period was shown to favorably alter body composition while concurrently increasing bone mass and serum free testosterone levels in overweight and obese men. The results indicate that forskolin is a possible therapeutic agent for the management and treatment of obesity.