PROPECIAHELP: Unresolved Finasteride Propecia Proscar side effects info & discussion forum

Forum for men with PERSISTENT sexual, mental & physical side effects which CONTINUE DESPITE QUITTING Finasteride (Propecia, Proscar), a 5AR inhibitor drug for hair loss, prostate enlargement & prostate cancer.
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 Post subject: Dopamine
PostPosted: Tue Dec 22, 2009 3:21 pm 
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Joined: Mon Nov 30, 2009 8:49 am
Posts: 45
Someone on this site mentioned how Post Fin Syndrom could cause low Dopamine.

How does that happen?

My whole body has a steay tremble like I have MS or Parkinsons. Its no very pronounced but I feel it and see it when I hold out a paper or am sitting.

No one else seems to be having the same side effect as me. I have the leg twitches but I have hhad that since I was a child.


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 Post subject:
PostPosted: Tue Dec 22, 2009 4:24 pm 
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Joined: Sun Aug 30, 2009 3:39 pm
Posts: 87
I think you are talking about your neurons being damaged along your spinal cord which was caused by the supression of dht.5ar2 is concetrated along the spinal cord when you supress it you are mimincing the affects of ms.I think you should be ok eventually once the motor neurons regenerate,thats my theory maybe im right who knows :?


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 Post subject:
PostPosted: Thu Dec 31, 2009 12:50 am 
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Joined: Thu Sep 17, 2009 8:23 am
Posts: 281
MS is not due to low dopamine. It's a demyelinating disoder. It doesn't specifically cause a tremor.

The three features of Parkinson's disease are

1. Bradykinesia (slow movement)
2. Rigidity
3. Pill rolling tremor (ie) between thumb and forefinger

Also, the above would be worsening over time should you have a Parkinsonian disease.

JN


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 Post subject: Just saw my Neurologist
PostPosted: Thu Dec 31, 2009 11:52 am 
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Joined: Mon Nov 30, 2009 8:49 am
Posts: 45
I now have Benign Essential Tremors.
Not sure what caused them but knowing it's not fatal helps my anxiety a lot!
Just wasted money on Mucuna Periens.
Not taking the L-Dopa anymore.
Trimming down my supplements.
Seeing my endo in 12 days.


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 Post subject:
PostPosted: Tue Jan 05, 2010 5:08 pm 
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Joined: Sat Dec 27, 2008 6:42 pm
Posts: 196
ScaredinMD,

I would give alex.miller's posts a careful read. Mew copied a couple of key ones here (search here), the remainder are on a har loss forum hairlosshelp.com.. He is a neurobiology student who located references indicating that long term 5AR2 suppression could lead to demylination of certain spinal chord nerves, at least in rats. This could be the source of your tremors (theorizing here).

5 alpha reductase (5AR2) deficiency reduces the conversion of progesterone into the neurotransmitter allopregnanelone. Test your progesterone levels as only research labs measure the latter.

Ask your endo to run a 3 alpha androstanediiol glucuronide test on you, then let us know the result. This is the best marker we have found for determining whether fin useage left us depleted in 5AR2 activity.

kazman


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