PROPECIAHELP: Persistent Finasteride Propecia Proscar side effects info & discussion forum

Forum for men with PERSISTENT sexual, mental & physical side effects which CONTINUE DESPITE QUITTING Finasteride (Propecia, Proscar), a 5AR inhibitor drug for hair loss, prostate enlargement & prostate cancer.
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dgreene
 Post subject: Shrinkage articles
PostPosted: Mon Jan 09, 2012 7:40 pm 
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Joined: Mon Aug 29, 2011 3:25 am
Posts: 597
Age: 24
Drug: Propecia
Usage: 4mths, 1wk
Started: 24 Jul 2011
Stopped: 29 Jul 2011
Location: USA
http://banpropecia.blogspot.com/
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tenyearuser
 Post subject: Re: Shrinkage articles
PostPosted: Sat Feb 11, 2012 7:46 am 
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Joined: Sun Feb 05, 2012 9:11 am
Posts: 95
Age: 50
Drug: Propecia
Usage: 10 years
Started: 01 Jan 1998
Stopped: 7- 0-2011
Location: los angeles
dgreene wrote:
http://banpropecia.blogspot.com/


holy crap. those two images say tons about at least part of what's occurred to us.
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Y-C
 Post subject: Re: Shrinkage articles
PostPosted: Sat Feb 11, 2012 10:41 pm 
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Joined: Wed Oct 21, 2009 2:22 pm
Posts: 112
"Note that PDE 5 inhibitors (sildenafil, tadalafil) can improve blood inflow (to some extent -- after tissue is lost it cannot relax smooth muscle that is no longer there) but will not repair leaky tunica albuginea. "

Does that mean that some muscle is destroyed in our penises?
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braziliandude
 Post subject: Re: Shrinkage articles
PostPosted: Sat Feb 11, 2012 11:01 pm 
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Joined: Sat Nov 26, 2011 8:21 pm
Posts: 457
Age: 20
Drug: Propecia
Usage: 1.2 years
Started: 0- 7-2010
Stopped: 0- 8-2011
Location: brazil
there are recoveries... so dont panick. i believe the muscle is weak however its not destroyed...they probably overdosed the rat with fin fdor a long time...it works differently in humans.
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prop
 Post subject: Re: Shrinkage articles
PostPosted: Sat Feb 11, 2012 11:43 pm 
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Joined: Wed Sep 01, 2010 3:47 am
Posts: 579
Age: 0
Location: europe
is possible have not a mere echodoppler, but a penile corpora cavernosa endoscopy/biopsy?

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boston332
 Post subject: Re: Shrinkage articles
PostPosted: Sun Feb 12, 2012 4:46 am 
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Joined: Thu Aug 12, 2010 3:54 am
Posts: 1339
Age: 0
Location: New York
There was a study performed at Wake Forest about 4 yrs showing it was theoretically possible to regrow penile tissue. Also, I remember a matrix type material from pigs has some some promise in rebuilding tissue. And hopefully stem cell treatments will improve over the next few years. Maybe out of one of those areas we'll come up with something.
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Y-C
 Post subject: Re: Shrinkage articles
PostPosted: Sun Feb 12, 2012 10:15 am 
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Joined: Wed Oct 21, 2009 2:22 pm
Posts: 112
Well, theoretically it is...we will be old men since long when this is available in practice.
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martinM
 Post subject: Re: Shrinkage articles
PostPosted: Mon Feb 13, 2012 8:22 am 
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Joined: Tue Mar 24, 2009 1:31 am
Posts: 1816
Age: 30
Drug: Propecia
Location: USA
braziliandude wrote:
i believe the muscle is weak however its not destroyed...they probably overdosed the rat with fin fdor a long time...it works differently in humans.


This is an assumption. If you have scientific evidence that finasteride functions differently on humans please post it. From your post it's also obvious that you haven't read the study as you didn't state the dosing in the rats.

I don't want to sound too harsh but this is obviously something an internet poster without complete information would state.
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braziliandude
 Post subject: Re: Shrinkage articles
PostPosted: Mon Feb 13, 2012 11:19 am 
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Joined: Sat Nov 26, 2011 8:21 pm
Posts: 457
Age: 20
Drug: Propecia
Usage: 1.2 years
Started: 0- 7-2010
Stopped: 0- 8-2011
Location: brazil
yes and this study also says they dont know what happened after stopping it.....sooo this is also not very reliable.
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martinM
 Post subject: Re: Shrinkage articles
PostPosted: Mon Feb 13, 2012 1:04 pm 
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Joined: Tue Mar 24, 2009 1:31 am
Posts: 1816
Age: 30
Drug: Propecia
Location: USA
The blog states:

Quote:
In conclusion, while I as a simple individual cannot categorically affirm that finasteride induced DHT inhibition causes corpus cavernosal changes leading to erectile dysfunction, I do believe that there is enough data, which has been present for many years, to suggest that this is possible. Anecdotal reports by urologists suggest that they see patients with persistent symptoms frequently (one every few weeks at major medical centers), both while on and after discontinuation of finasteride, suggesting that this is a widespread problem that is underreported due to either embarrassment or ignorance. It is possible that as men who were previously exposed to finasteride without – at present – symptoms of sexual dysfunction grow older, corpus cavernosal structural changes in these men will cause them to have much earlier onset of ‘normal’ erectile dysfunction, as they have decreased residual/reserve function.


you state:

Quote:
i believe the muscle is weak however its not destroyed...they probably overdosed the rat with fin fdor a long time...it works differently in humans.


See the difference?
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Broken_Pecker
 Post subject: Re: Shrinkage articles
PostPosted: Sat Feb 25, 2012 4:15 pm 
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Joined: Sat Jan 22, 2011 8:35 pm
Posts: 1223
Age: 29
Drug: Propecia
Usage: Off and on
Started: 15 Jan 2006
Stopped: 27 Jun 2006
Location: Kenneth Frazier's House
That is some very good scientific data on that page, we should have that article stickied on this site if it already isn't somewhere.

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Fanjeera
 Post subject: Re: Shrinkage articles
PostPosted: Tue Mar 20, 2012 1:07 pm 
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Joined: Wed Jun 17, 2009 4:20 pm
Posts: 485
http://www.asiaandro.com/archive/1008-682X/5/33.htm
The images come from here. We can't make any conclusions based on rats who were treated with massive amounts of fin for 4 weeks. It's an old study and its goal was different.
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