Post-Androgen Deprivation Syndrome
Diverse substances capable of anti-androgenic endocrine disruption including 5alpha reductase inhibitors, isotretinoin, serotonergic antidepressants, saw palmetto extract and concentrated phenolic compounds marketed as health supplements are causing a severe syndrome in some consumers. The administrators of propeciahelp have provided a literature review and mechanistic hypothesis to inform further clinical research.
Blog
New publication reports penile vascular abnormalities in the majority of Post-Finasteride Syndrome patients
In a newly released publication, a clinical study at the Baylor College of Medicine reported penile vascular abnormalities in the majority of PFS patients.
A word on Covid-19
Dear members, As you are all aware the world has entered a very uncertain period due to the Covid-19 pandemic. The novel coronavirus is presenting a serious challenge to the healthcare systems of advanced countries, and the safety of the…
A Post-Androgen Deprivation Syndrome: A literature review
Some patients develop persistent and severe multisystemic health problems following exposure to the 5 alpha reductase inhibitor finasteride. Serious and permanent harm is not correlated positively to exposure and can follow as little as one dose. This has been termed…
New publications focus attention on devastating consequences of PFS
Two new publications centred on PFS have been published, and serve to highlight many of the urgent challenges faced clinically and scientifically in adequately addressing the condition. Finasteride and Suicide: A postmarketing case series Writing in Dermatology, Professor Irwig carefully…
Round-up of 2019 – We Got Good Work Done Together
2019 was an important year for Propeciahelp.com and our forum contributors. Here’s a quick round-up of our three key achievements: Relaunch of Propeciahelp.com We’ve gone from a website largely dormant and with low use of the forum – to a revamped website,…
Guerrilla Patient Group Publishes Data Insights into Post-Drug Syndrome
The reports are steady. The stories are raw and difficult. The problem of lasting physical, sexual and neuro-cognitive health damage from mass market medication has been known about for years. Yet doctors continue to fail their patients and have no idea how to…
Latest Research
- Are finasteride-related penile curvature/Peyronie's disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases
A limited number of studies have described patients on finasteride showing findings which were consistent with Peyronie's disease (PD). We aimed to detect a pharmacovigilance signal of possible a … - Sexual side effects from treatment with SSRI
Treatment with SSRI have a high frequency of treatment of emergent sexual dysfunction. The mechanism is thought to be through serotoninergic inhibition of the sexual response. More than 70% of patient … - Lasers, lights, and compounds for hair loss in aesthetics
Hair loss is a common complaint that is often stressful for patients and a challenge for practitioners to treat. Fortunately, innovations in the field have contributed to growing evidence for several … - Pharmacological Management of Pattern Hair Loss
Pattern hair loss (PHL) is a condition that worsens with time and the only way it can be slowed down is with pharmacological intervention. Pharmacological treatments for PHL, from an evidenced-based p … - 5-Alpha reductase inhibitor related litigation: A legal database review
CONCLUSION: 5α-reductase inhibitor was alleged to have sexual, mental, and physical side effects, resulting in legal litigation. Despite this, no judgment against a physician or pharmaceutical company …