The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

Join the Community

The site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

previous arrowprevious arrow
next arrownext arrow


Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects

July 9, 2018 - Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage, gynecomastia, muscle atrophy, cognitive impairment, insomnia, severely dry skin and tinnitus. The condition often has a radical and extreme impact - Continue Reading »

Relaunch of

May 19, 2018 - Welcome to both long term sufferers of PFS and new members. Propeciahelp has now undergone a substantial update. This change was necessary from a technical perspective, but also for a number of reasons relating to user experience, including the accommodation of mobile devices. We hope that you find the new design pleasant and easy to navigate. As well as a - Continue Reading »

Ongoing research into PFS

May 19, 2018 - PFS is a variable and potentially devastating condition, but its molecular mechanism(s) are currently unclear. The predispositions that cause a subset of men to develop PFS from as little as a single exposure to a 5-alpha reductase inhibitor remain unknown. Reported symptoms include (but are not limited to) loss of libido, erectile dysfunction, suicidal ideation, depression, anxiety, panic attacks, cognitive - Continue Reading »

Latest Forum Topics

  • How to realistically ween / taper off Finasteride?
    by @Tony on July 16, 2018 at 8:06 pm

    @Tony wrote: Hi all I’ve been on 1.00 and later 1.25 mg Finasteride daily for about 15-18 years now (I’m 44 years old) and I added Dustaride (once a week ) to the mix, about a year ago. I now want to stop taking both because I’m often […]

  • Anyone try BPC 157 or other healing peptides?
    by @Devolution on July 16, 2018 at 6:48 pm

    @Devolution wrote: Hey guy’s as a lot of you know now my skin is still deteriorating body wide with ehlers danlos elasticity type symthoms, poor wound healing/repair, thinning of the skin, hard/broken down subcutaneous wastage/dermal tissue not […]

  • Is inflammation something to avoid?
    by @Greek on July 16, 2018 at 5:31 pm

    @Greek wrote: I assume inflammation is bad news for us. I don’t really know why, i just assumed. However, I just read that inflammation is part of the body’s method for dealing with problems. I have not looked deeply into this at all. It […]

  • Do you drink alcohol?
    by @Greek on July 16, 2018 at 4:38 am

    @Greek wrote: Do you drink alcohol? Does it have a positive/negative/any effect on your condition? Posts: 6 Participants: 4 Read full topic […]

  • Frequent urination/urinary incontinence is driving me crazy
    by @Wings on July 16, 2018 at 4:02 am

    @Wings wrote: I made a post a few months back about having frequent urination. I’ve had it for about a year now. I always have to get up at night to go. I almost always feel like I have to pee. When I do go, not 10-20 minutes later do I have […]

Close Menu