The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site

propeciahelp.com is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The propeciahelp.com site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Memory disorders “significantly associated” with isotretinoin and antidepressant use

Memory disorders “significantly associated” with SSRI and isotretinoin use Memory disorders and related problems are a key concern of Propeciahelp.com members.  French researchers, publishing in the British Journal of Clinical Pharmacology, have found that both isotretinoin and antidepressants are  significantly associated with memory disorders:…

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Elle magazine covers devastating persistent effects

Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage,…


Latest Forum Topics

  • A very confusing and depressing story.... PLEASE HELP
    by @Baldie on August 21, 2019 at 8:00 am

    @Baldie wrote: Hello, Sorry for the weird title. I had no idea what to write. My story begins 8 years ago when my girlfriend took me to a doctor to treat my hairfall. He gave me 10% minoxidal, a shampoo and a pill. I have no idea what those pills were […]

  • Why methylation is key to recovery
    by @MasterofPuppets on August 21, 2019 at 4:48 am

    @MasterofPuppets wrote: Methyl donors such as B vitamins choline and betaine are what your liver uses to remove estrogen from your body even “estrogen blockers” will not remove estrogen from your body. (The only estrogen blockers that […]

  • Activation of the Androgen Receptor by Butyrate
    by @MOONCHILD on August 21, 2019 at 1:25 am

    @MOONCHILD wrote: Ligand-independent Activation of the Androgen Receptor by the Differentiation Agent Butyrate in Human Prostate Cancer Cells Cancer Research – 15 Oct 00 Ligand-independent Activation of the Androgen Receptor by the […]

  • Testicular microbiome
    by @guitarman01 on August 21, 2019 at 12:26 am

    @guitarman01 wrote: The study doesn’t really matter much to me atm. Its the fact that its there. this is the first study to outline that the testis holds tissue-associated commensal bacteria Testicular microbiome and dysbiosis These analyses show […]

  • Epigenetics, Gene Expression, and the Astronaut
    by @guitarman01 on August 20, 2019 at 3:59 pm

    @guitarman01 wrote: @axolotl A pretty cool, simple article looking at some of this. I also realized you werent talking about gene changes at the dna level looking back at your post. This could almost be tucked under your methylation thread. Also notice […]


Latest Research

  • Post-finasteride syndrome.
    Related Articles Post-finasteride syndrome. BMJ. 2019 Aug 09;366:l5047 Authors: Gray SL, Semla TP PMID: 31399423 [PubMed – in process]
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