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Memory disorders “significantly associated” with isotretinoin and antidepressant use
Memory disorders “significantly associated” with SSRI and isotretinoin use Memory disorders and related problems are a key concern of Propeciahelp.com members. French researchers, publishing in the British Journal of Clinical Pharmacology, have found that both isotretinoin and antidepressants are significantly associated with memory disorders:…
Important Announcement: Two Community-Led Research Projects – Please Participate
We are today announcing two significant community-led scientific projects, both requiring the contributions of patients suffering Post-Finasteride Syndrome and the persistent conditions caused by use of isotretinoin (accutane), dutasteride (avodart) and saw palmetto (other 5 alpha reductase inhibiting substances) as…
Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects
Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage,…
Relaunch of propeciahelp.com
Welcome to both long term sufferers of PFS and new members. Propeciahelp has now undergone a substantial update. This change was necessary from a technical perspective, but also for a number of reasons relating to user experience, including the accommodation…
Ongoing research into PFS
PFS is a variable and potentially devastating condition, but its molecular mechanism(s) are currently unclear. The predispositions that cause a subset of men to develop PFS from as little as a single exposure to a 5-alpha reductase inhibitor remain unknown….
Latest Forum Topics
- Do confirm that what I have assumed is like Finasteride or worse? by @Kitsunebi88 on October 14, 2018 at 1:42 pm
@Kitsunebi88 wrote: “We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved in quercetin-mediated downregulation of AR activity. Transient […]
- Many studies have found that AR activation by @Kitsunebi88 on October 14, 2018 at 1:42 am
@Kitsunebi88 wrote: “Androgen receptor (AR) signaling pathway is required for both development of normal prostate gland and prostate cancer (PC). Patient with advanced disease are usually treated with androgen deprivation therapy. However, this […]
- Masturbation Downregulates Certain Androgenic Receptors [in The Brain] And Upregulates Certain Estro by @Kitsunebi88 on October 14, 2018 at 1:13 am
@Kitsunebi88 wrote: A few interesting rat studies. ncbi.nlm.nih.gov Increased estrogen receptor alpha immunoreactivity in the forebrain of sexually satiated rats. BV Phillips-Farfán, AE Lemus and A Fernández-Guasti, Hormones […]
- I took 2 1mg Finasteride pills 1+ month ago by @Joker on October 13, 2018 at 5:59 pm
@Joker wrote: Hey guys. Just signed up. I just wanted to share my story. On the 6th of September (37 days ago) I took my first finasteride. I noticed my balls felt weird later that night. 24 hours later I decided to take another. The […]
- Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase by @Kitsunebi88 on October 13, 2018 at 4:13 pm
@Kitsunebi88 wrote: Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1. "Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of […]