Post-Androgen Deprivation Syndrome
Diverse substances capable of anti-androgenic endocrine disruption including 5alpha reductase inhibitors, isotretinoin, serotonergic antidepressants, saw palmetto extract and concentrated phenolic compounds marketed as health supplements are causing a severe syndrome in some consumers. The administrators of propeciahelp have provided a literature review and mechanistic hypothesis to inform further clinical research.
Blog
New publication reports penile vascular abnormalities in the majority of Post-Finasteride Syndrome patients
In a newly released publication, a clinical study at the Baylor College of Medicine reported penile vascular abnormalities in the majority of PFS patients.
A word on Covid-19
Dear members, As you are all aware the world has entered a very uncertain period due to the Covid-19 pandemic. The novel coronavirus is presenting a serious challenge to the healthcare systems of advanced countries, and the safety of the…
A Post-Androgen Deprivation Syndrome: A literature review
Some patients develop persistent and severe multisystemic health problems following exposure to the 5 alpha reductase inhibitor finasteride. Serious and permanent harm is not correlated positively to exposure and can follow as little as one dose. This has been termed…
New publications focus attention on devastating consequences of PFS
Two new publications centred on PFS have been published, and serve to highlight many of the urgent challenges faced clinically and scientifically in adequately addressing the condition. Finasteride and Suicide: A postmarketing case series Writing in Dermatology, Professor Irwig carefully…
Round-up of 2019 – We Got Good Work Done Together
2019 was an important year for Propeciahelp.com and our forum contributors. Here’s a quick round-up of our three key achievements: Relaunch of Propeciahelp.com We’ve gone from a website largely dormant and with low use of the forum – to a revamped website,…
Guerrilla Patient Group Publishes Data Insights into Post-Drug Syndrome
The reports are steady. The stories are raw and difficult. The problem of lasting physical, sexual and neuro-cognitive health damage from mass market medication has been known about for years. Yet doctors continue to fail their patients and have no idea how to…
Latest Research
- Finasteride for hair loss: A review
BACKGROUND AND OBJECTIVES: Finasteride 1 mg/day is indicated for androgen-dependent conditions such as male androgenetic alopecia (AGA). - Differential Gene Expression in Post-Finasteride Syndrome Patients
CONCLUSION: This study is the first to consider and demonstrate gene expression differences in patients with PFS as a potential etiology of sexual dysfunction. Howell S, Song W, Pastuszak A, et al. Di … - Exposure to serotonin selective reuptake inhibitors or serotonin noradrenaline reuptake inhibitors and sexual dysfunction: Results from an online survey
CONCLUSIONS: Based on the present results, PSSD is a complex iatrogenic syndrome in need of being further studied and understood. - Alterations of gut microbiota composition in post-finasteride patients: a pilot study
CONCLUSION: Gut microbiota population is altered in PFS patients, suggesting that it might represent a diagnostic marker and a possible therapeutic target for this syndrome. - Finasteride Use Is Associated with Higher Odds of Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System
Finasteride is a 5-α reductase inhibitor indicated for the treatment of androgenetic alopecia and benign prostatic hyperplasia (BPH). Finasteride has been associated with various adverse events, such …