The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Memory disorders “significantly associated” with isotretinoin and antidepressant use

Memory disorders “significantly associated” with SSRI and isotretinoin use Memory disorders and related problems are a key concern of members.  French researchers, publishing in the British Journal of Clinical Pharmacology, have found that both isotretinoin and antidepressants are  significantly associated with memory disorders:…

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects

Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage,…

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    by @kon93 on October 17, 2018 at 6:51 am

    @kon93 wrote: The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation. R Frau, V Bini, A Soggiu, S Scheggi, A Pardu, S Fanni, P Roncada, M Puligheddu, F Marrosu, D Caruso, P […]

  • Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors
    by @Sibelio on October 17, 2018 at 5:29 am

    @Sibelio wrote: Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors. ER Coskuner, B Ozkan and MG Culha, Sexual medicine reviews, Oct 2018 06 5-Alpha reductase inhibitors (5-ARIs) […]

  • Safety concerns when using novel medications to treat alopecia
    by @Sibelio on October 17, 2018 at 5:09 am

    @Sibelio wrote: Safety concerns when using novel medications to treat alopecia. HM Almohanna, M Perper and A Tosti, Expert opinion on drug safety, Oct 2018 13 Alopecia is often a cause of great concern to patients for […]

  • Has anyones head pressure improved over time or with supplements?
    by @Shellnyce on October 16, 2018 at 9:10 pm

    @Shellnyce wrote: My biggest sort of “sides” are head pressure that seems to come and go. Sometimes it seems like it’s brought on by walking or moving. Sometimes working out or eating a salad seems to improve it. The pressure […]

  • Gut crash every after ejaculation
    by @KeepingHard on October 16, 2018 at 6:51 pm

    @KeepingHard wrote: Hi guys I would like to share with you a recurring situation that I think is damaging me (or doesn’t let me recover). Since I crashed, more than 4 years ago, I have always had gut problems. I’ve never done anything to […]

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