The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Important Announcement: Two Community-Led Research Projects – Please Participate

August 15, 2018 - We are today announcing two significant community-led scientific projects, both requiring the contributions of patients suffering Post-Finasteride Syndrome and the persistent conditions caused by use of isotretinoin (accutane), dutasteride (avodart) and saw palmetto (other 5 alpha reductase inhibiting substances) as well as SSRI class antidepressants and leuprorelin (lupron). Please read on for details of these initiatives and how you can - Continue Reading »

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects

July 9, 2018 - Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage, gynecomastia, muscle atrophy, cognitive impairment, insomnia, severely dry skin and tinnitus. The condition often has a radical and extreme impact - Continue Reading »

Relaunch of

May 19, 2018 - Welcome to both long term sufferers of PFS and new members. Propeciahelp has now undergone a substantial update. This change was necessary from a technical perspective, but also for a number of reasons relating to user experience, including the accommodation of mobile devices. We hope that you find the new design pleasant and easy to navigate. As well as a - Continue Reading »

Ongoing research into PFS

May 19, 2018 - PFS is a variable and potentially devastating condition, but its molecular mechanism(s) are currently unclear. The predispositions that cause a subset of men to develop PFS from as little as a single exposure to a 5-alpha reductase inhibitor remain unknown. Reported symptoms include (but are not limited to) loss of libido, erectile dysfunction, suicidal ideation, depression, anxiety, panic attacks, cognitive - Continue Reading »

Latest Forum Topics

  • Low local estrone ipotrichia or... just inflammation?
    by @Go_gaster_Sonic on August 18, 2018 at 1:53 pm

    @Go_gaster_Sonic wrote: Here’s a part of the story that you don’t know. My first dermatologist made a huge mistake telling me that i have an androgenetic alopecia and giving me propecia, indeed i don’t have it. i took finasteride […]

  • Borax - SSRI/Finasteride user
    by @borax on August 18, 2018 at 10:20 am

    @borax wrote: Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation. Where are you from (country)? India, live in the UAE. How did you find this […]

  • DIM or Resveratol
    by @BP86 on August 18, 2018 at 5:28 am

    @BP86 wrote: I’m thinking of adding one of these two to my stack. I’ve heard that both can inhibit the 5-AR, but I’ve also heard that this effect is minimal and that they can help to balance hormones. My E is in range at 29.8 […]

  • My Accutane (Absorbica) Story
    by @BearOf17 on August 18, 2018 at 3:44 am

    @BearOf17 wrote: Where are you from (country)? United States How did you find this forum (Google search – if so, what search terms? Via link from a forum or website – if so, what page? Other?) From being on the forum […]

  • Going out with friends is a pain
    by @Go_gaster_Sonic on August 17, 2018 at 7:08 pm

    @Go_gaster_Sonic wrote: I noticed that i don’t really want to go out with friends. Only the idea of going out with friends makes me feel very anxious and when i’m out with them, i just want to go back home as soon as possible, i don’t […]

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