Post-Androgen Deprivation Syndrome
Diverse substances capable of anti-androgenic endocrine disruption including 5alpha reductase inhibitors, isotretinoin, serotonergic antidepressants, saw palmetto extract and concentrated phenolic compounds marketed as health supplements are causing a severe syndrome in some consumers. The administrators of propeciahelp have provided a literature review and mechanistic hypothesis to inform further clinical research.
Blog
New publication reports penile vascular abnormalities in the majority of Post-Finasteride Syndrome patients
In a newly released publication, a clinical study at the Baylor College of Medicine reported penile vascular abnormalities in the majority of PFS patients.
A word on Covid-19
Dear members, As you are all aware the world has entered a very uncertain period due to the Covid-19 pandemic. The novel coronavirus is presenting a serious challenge to the healthcare systems of advanced countries, and the safety of the…
A Post-Androgen Deprivation Syndrome: A literature review
Some patients develop persistent and severe multisystemic health problems following exposure to the 5 alpha reductase inhibitor finasteride. Serious and permanent harm is not correlated positively to exposure and can follow as little as one dose. This has been termed…
New publications focus attention on devastating consequences of PFS
Two new publications centred on PFS have been published, and serve to highlight many of the urgent challenges faced clinically and scientifically in adequately addressing the condition. Finasteride and Suicide: A postmarketing case series Writing in Dermatology, Professor Irwig carefully…
Round-up of 2019 – We Got Good Work Done Together
2019 was an important year for Propeciahelp.com and our forum contributors. Here’s a quick round-up of our three key achievements: Relaunch of Propeciahelp.com We’ve gone from a website largely dormant and with low use of the forum – to a revamped website,…
Guerrilla Patient Group Publishes Data Insights into Post-Drug Syndrome
The reports are steady. The stories are raw and difficult. The problem of lasting physical, sexual and neuro-cognitive health damage from mass market medication has been known about for years. Yet doctors continue to fail their patients and have no idea how to…
Latest Research
- Cutting the First Turf to Heal Post-SSRI Sexual Dysfunction: A Male Retrospective Cohort Study
Post-SSRI sexual dysfunction (PSSD) is a set of heterogeneous sexual problems, which may arise during the administration of selective serotonin reuptake inhibitors (SSRIs) and persist after their disc … - Global online interest in finasteride sexual side effects
Prior literature has suggested that finasteride may negatively impact men's sexual health. In 2011, the Food and Drug Administration (FDA) provided a warning on finasteride drug labels to incorpo … - Post-Finasteride Syndrome. Literature Review
CONCLUSIONS: Finasteride is rarely associated with sexual and systemic adverse effects that constitute the so-called post-finasteride syndrome. There are still few studies on this syndrome in the worl … - Are finasteride-related penile curvature/Peyronie's disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases
A limited number of studies have described patients on finasteride showing findings which were consistent with Peyronie's disease (PD). We aimed to detect a pharmacovigilance signal of possible a … - Sexual side effects from treatment with SSRI
Treatment with SSRI have a high frequency of treatment of emergent sexual dysfunction. The mechanism is thought to be through serotoninergic inhibition of the sexual response. More than 70% of patient …