The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Memory disorders “significantly associated” with isotretinoin and antidepressant use

Memory disorders “significantly associated” with SSRI and isotretinoin use Memory disorders and related problems are a key concern of members.  French researchers, publishing in the British Journal of Clinical Pharmacology, have found that both isotretinoin and antidepressants are  significantly associated with memory disorders:…

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects

Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage,…

Latest Forum Topics

  • I feel extremely bad
    by @Damon on January 23, 2019 at 11:23 pm

    @Damon wrote: Tonight I feel extremely bad… I’m thinking about how to die… I wish I had at least a fucking improvement They are totally without any hope This damn PFS is really terrible… Posts: 1 […]

  • PSSD and anhedonia
    by @sue_denim on January 23, 2019 at 10:33 pm

    @sue_denim wrote: Hi guys, I’m a 26 year old female who has been suffering with severe PSSD and anhedonia since mid 2014. I stupidly cold-turkeyed 150mg of Sertraline and I’ve been paying the price for that ever since. I have never had […]

  • I think I'm ending it very soon
    by @Wetaka on January 23, 2019 at 9:09 pm

    @Wetaka wrote: It’s just been 3 weeks of the drug technically, but things are so fucking tough right now and I don’t see any way out of this besides suicide. I don’t wanna see how my symptoms get worse each day, how I’m a […]

  • Lifting Weights
    by @lakehouse on January 23, 2019 at 6:36 pm

    @lakehouse wrote: If 95% of my sides are mental (5% unnoticeable other sides to be safe), then would it be safe to lift weights? I was lifting for a few months last year and didn’t notice anything. Recently was doing cardio for a few months […]

  • Overview at Baylor On PFS..Precusor to Epigenetic Study?
    by @holyhead on January 23, 2019 at 3:54 pm

    @holyhead wrote: Just ran across this forgive if its been posted before… Posts: 6 Participants: 5 Read full topic […]

Latest Research

  • Post-finasteride syndrome – does it really exist?
    Related Articles Post-finasteride syndrome – does it really exist? Aging Male. 2019 Jan 16;:1-10 Authors: Maksym RB, Kajdy A, Rabijewski M Abstract Inhibitors of 5α-steroid reductase are drugs used to …
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