The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

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propeciahelp.com is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The propeciahelp.com site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Memory disorders “significantly associated” with isotretinoin and antidepressant use

Memory disorders “significantly associated” with SSRI and isotretinoin use Memory disorders and related problems are a key concern of Propeciahelp.com members.  French researchers, publishing in the British Journal of Clinical Pharmacology, have found that both isotretinoin and antidepressants are  significantly associated with memory disorders:…

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Elle magazine covers devastating persistent effects

Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage,…


Latest Forum Topics

  • Bad sexuality and other side-effects from Fluoxetine, Risperidone and Abilify
    by @MatthiasKDH on September 18, 2019 at 2:25 am

    @MatthiasKDH wrote: Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation. Where are you from (country)? G How did you find this forum (Google […]

  • Not sure if have PFS (Depression, ansiety, porn usage?)... I'm desperate!
    by @Omega123 on September 18, 2019 at 1:15 am

    @Omega123 wrote: Hello, guys! I have a story to tell and I’m not sure if I have PFS. I’m 25 year old male and I took finasteride 1 mg form 19 to 24 (almost 25), which I did for 12 months in a row and then “resting” for 1 month. […]

  • Psilocybin/Ketamine
    by @borax on September 17, 2019 at 8:12 pm

    @borax wrote: Has anyone here had experience with Ketamine or Psilocybin? If so: -Have you had any improvement in symptoms? -Did you microdose or take a regular dose? Posts: 4 Participants: 3 Read full […]

  • Judge Brian Cogan
    by @trav on September 17, 2019 at 6:04 pm

    @trav wrote: Brian Cogan is the judge who if I’m not mistaken is in charge of deciding whether or not the Merck sealed documents that Reuter’s recently filed a court order for. This seems to be a great opportunity for a massive upheaval and […]

  • Thoughts on the mechanism of Post-Drug Syndrome
    by @arkaeik on September 17, 2019 at 5:19 pm

    @arkaeik wrote: Note: I am not stating that the following is true, this is only a theory. Unfortunately I don’t have the scientific vocabulary to describe it perfectly. The body is deprived of a specific endogenous substance. In PFS, PSSD, PAS […]


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