The Post-Finasteride Syndrome (PFS)

PFS describes a life-altering condition that can develop in a subset of men following exposure to the 5-alpha reductase inhibitor Finasteride (Propecia)

About this site is a website and discussion forum for men suffering persistent sexual, mental & physical effects after taking the drug Finasteride

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The site and discussion forum exists to support and connect men affected by the Post-Finasteride Syndrome

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Important Announcement: Two Community-Led Research Projects – Please Participate

August 15, 2018 - We are today announcing two significant community-led scientific projects, both requiring the contributions of patients suffering Post-Finasteride Syndrome and the persistent conditions caused by use of isotretinoin (accutane), dutasteride (avodart) and saw palmetto (other 5 alpha reductase inhibiting substances) as well as SSRI class antidepressants and leuprorelin (lupron). Please read on for details of these initiatives and how you can - Continue Reading »

Accutane: Journalist seeks interviewees for isotretinoin side effects research, UK issues drug safety update and Cosmo magazine covers devastating persistent effects

July 9, 2018 - Accutane (isotretinoin) shares potent 5-alpha reductase inhibiting properties with finasteride and can cause a syndrome that can be apparently identical to Post Finasteride Syndrome. Reported persistent effects include libido loss, erectile dysfunction, depression, suicidal ideation, anxiety, panic attacks, penile shrinkage, gynecomastia, muscle atrophy, cognitive impairment, insomnia, severely dry skin and tinnitus. The condition often has a radical and extreme impact - Continue Reading »

Relaunch of

May 19, 2018 - Welcome to both long term sufferers of PFS and new members. Propeciahelp has now undergone a substantial update. This change was necessary from a technical perspective, but also for a number of reasons relating to user experience, including the accommodation of mobile devices. We hope that you find the new design pleasant and easy to navigate. As well as a - Continue Reading »

Ongoing research into PFS

May 19, 2018 - PFS is a variable and potentially devastating condition, but its molecular mechanism(s) are currently unclear. The predispositions that cause a subset of men to develop PFS from as little as a single exposure to a 5-alpha reductase inhibitor remain unknown. Reported symptoms include (but are not limited to) loss of libido, erectile dysfunction, suicidal ideation, depression, anxiety, panic attacks, cognitive - Continue Reading »

Latest Forum Topics

  • Sleep Improvement - for those who wake at night and then go back to sleep
    by @Greek on August 20, 2018 at 7:08 am

    @Greek wrote: My sleep has improved significantly. I don’t have any real problems in going to sleep at the end of the day now. In terms or amount of sleep, I’ve gone from zero to two hours a night, to something like a total of 8 hours per […]

  • Pregnenolone and temporary improvement in muscle tone and cognition
    by @Andrea on August 19, 2018 at 5:05 pm

    @Andrea wrote: I have taken pregnenolone 100mg/day for several days and everytime I experienced a significant improvement in muscle tone and cognition for a couple of hours. The only side effects in my case are pruritus and eczema. […]

  • New Member Recently Stopped Taking Finastride - Major Post Side Effects - Advice Appreciated
    by @Worrier77 on August 19, 2018 at 2:22 pm

    @Worrier77 wrote: Welcome to our community. Please fill in the following template as a way of introducing yourself, and helping others to understand your background and situation. Where are you from (country)? USA How did you find this forum (Google […]

  • Endocrine Disruptors: The bigger picture
    by @awor on August 19, 2018 at 7:57 am

    @awor wrote: You’re right, the name needs to be changed Post Androgenic Syndrome, those posts about fungal cream and soy drugs today really makes you realize the vast anti-androgen products out there. It still doesn’t cover all things […]

  • Worse symptoms in morning?
    by @gents93 on August 19, 2018 at 3:50 am

    @gents93 wrote: I seem to feel worse in the morning and much better at night. For example, in the morning my anxiety and depression is more prevalent. Libido is also less. By night, I have zero anxiety and no depression. Anyone else experience the same […]

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