Conclusion

Post-Finasteride Syndrome represents a Post-Androgen Deprivation Syndrome following exposure to antiandrogenic endocrine disruptors and without specificity to finasteride. The common pharmacological interruption of steroid signaling and remarkably similar clinical endpoints…

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The role of the AR in areas relevant to the neurological and psychological symptoms of PFS

Cognitive dysfunction, Anhedonia and Anxiety Anxiety, loss of motivation, loss of aggression, lack of feelings of wellbeing, severe anhedonia and visuospatial and cognitive impairment are some the most frequent neuropsychological…

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The role of the AR in areas relevant to the sexual dysfunction in PFS

Libido, erectile function, and penile structural maintenance Male libido and sexual desire is primarily androgen-mediated and strictly testosterone dependent. Considerable evidence supports libido loss as the clearest symptom of hypogonadism…

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PFS: Manifestation of a Post-Androgen Deprivation Syndrome following exposure to substances with antiandrogenic effects

Endocrine disruption "Endocrine disruption" refers to a specific toxicity whereby natural and/or anthropogenic chemicals cause adverse health effects by disrupting the endogenous hormone system. An endocrine disruptor is defined by…

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